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Modvigil 200mg increases wakefulness via influencing brain neurotransmitters. However, adverse impacts like stress, sleep deprivation, or appetite loss might have an indirect impact on immunity and general health. There have been sporadic reports of cutaneous or allergy responses that affect the immune system but do not signify immune suppression. See a medical expert for a thorough assessment if you take Modvigil 200 and have frequent infections or strange symptoms.